Chemiluminescent Detection of Active Oxygen Species, Singlet Molecular Oxygen and Superoxide, Using Cypridina Luciferin Analogues.
نویسندگان
چکیده
منابع مشابه
Enhancement of fluoresceinyl cypridina luciferin analog chemiluminescence by human serum albumin for singlet oxygen detection.
Fluoresceinyl cypridina luciferin analog (FCLA) is a chemiluminescence (CL) probe for detecting reactive oxygen species (ROS). Its efficiency for detecting singlet oxygen (1O2) can be significantly enhanced in the presence of human serum albumin (HSA). This phenomenon may apply to important applications for both research and clinical testing, because of the broad presence of HSA in the human sy...
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Three potential routes to generation of reactive oxygen species from α-tocopherolquinone have been identified. The quinone of the water-soluble vitamin E analogue Trolox C (Trol-Q) is reduced by hydrated electron and isopropanol α-hydroxyalkyl radical, and the resulting semiquinone reacts with molecular oxygen to form superoxide with a second order rate constant of 1.3 x 10 dm mol s, illustrati...
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Metabolism of molecular oxygen in the human body inevitably produces reactive oxygen species (ROS). Among the family of ROS, those exhibiting very high reactivities, including _OH, _OOH, ONOO , HOCl, HOBr, and O2, remain relatively underexplored. While emerging evidence suggests that these ROS are critically involved in physiological function as well as the genesis and development of diseases, ...
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Direct excitation at 1064 nm and detection of singlet molecular oxygen at 1270 nm is made possible by the availability of powerful YAG-lasers and sensitive NIR photomultipliers. Singlet oxygen was generated in condensed phase at 77 K by direct excitation at 1064 nm (without the use of sensitizers). Several luminescing species were observed by time resolved luminescence spectroscopy and luminesc...
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ژورنال
عنوان ژورنال: NIPPON SUISAN GAKKAISHI
سال: 1991
ISSN: 1349-998X,0021-5392
DOI: 10.2331/suisan.57.1711